Aspirin

Posted by: Stephen B on 14 April 2005

Well guys, I'm approaching 50, and according to recent news I should start taking aspirin to prevent a heart attack or stroke.

I exercise regularly, cycle, walk, swim (exept when I'm not feeling well due to colds), I eat wholemeal bread, oats for breakfast, at least 5 portions of fruit and veg daily, occasional red wine, avoid hydrogenated fats, limit refined sugar, and I eat oily fish twice a week.

Do I really need to start taking aspirin or other medication (eg. Cholesterol reducing statins) to prevent cardiovascular disease?

Do other forum members take any of the above measures in the hope of preventing heart disease and thereby increasing life expectancy?
Posted on: 24 April 2005 by djorg
http://www.supersmart.com/dev/productdetail.php?lang=fra&id=605
Winker
Posted on: 24 April 2005 by rodwsmith
Much more fun to get it from the wine though Djorg.

It has been a lengthy process to get it into pill form, but one of the reasons the work was done was that this natural elixir is also now known to help sufferers of leukaemia. Most of whom are not especially good candidates for drinking gallons of red wine.
Posted on: 24 April 2005 by Rasher
quote:
Originally posted by djorg:
...But don't forget Statins, which are probably the most effective medics for coronary syndromes prevention..

Eek Statins can be responsible for muscle cell damage and strange things happening with the liver & kidneys. There have been loads of deaths from rhabdomyolysis which lead to Baycol being withdrawn - but the effect is common to all statins. 82mg is the recommended daily dose of asprin to prevent cardiac problems and I would much rather take my chances with that thanks.
Posted on: 24 April 2005 by pe-zulu
quote:
Originally posted by Rockingdoc:
Self-medicating with aspirin in the absence of any cardiac history is not recommended.
Diet and exercise are safer options.


Yes, you are right, but diet and especially exercise demands much more self control in our age.
Posted on: 24 April 2005 by djorg
Rasher
You are right statins can be responsible for muscle cell damage (call myopathy) and it's true that statins can be responsible for some liver damage...but nothing about kidney! More, fatal rhabdomyolysis exist, its frequency is 2/1000 000 patients treated...

Aspirin adverse effects exist and are probably underestimated and how many patients present fatal gastro-intestinal bleeding under aspirin...

Does an effective treatment, without adverse effects exist?

Pe-Zulu:
you are right! a good diner, statin pill and everything is ok... We are dreaming Big Grin
Posted on: 24 April 2005 by Keith Tish
Okay, how about some facts.

1) The effect of Aspirin is different if you are male or female, no one knows why.

2) Women: 100mg aspirin/day reduces the risk of stroke by 17% compared to placebo, only if over 65yrs old. No effect on Heart attacks.

New England Journal Medicine March 31, 2005

3) Men: On aspirin 325mg alternate days.There was a 44 percent reduction in the risk of myocardial infarction in the aspirin group (254.8 per 100,000 per year as compared with 439.7 in the placebo group). A slightly increased risk of stroke among those taking aspirin was not statistically significant No reduction in mortality from all cardiovascular causes was associated with aspirin. Further analyses showed that the reduction in the risk of myocardial infarction was apparent only among those who were 50 years of age and older.

NEJM July 20, 1989

So, aspirin reduces MI in men over 50 and stroke in women over 65. However there are lots of other things that can/need to be addressed which will make a much larger difference to your chances of having an MI/stroke. How about family history, smoking, body weight, high blood pressure, diabetes, cholesterol level and irregular heart beat.

Taking aspirin is not an excuse to ignore all these other things. You will have to take responsibility for yourself and if that means eating and drinking less to lose weight, control your diabetes or high blood pressure, sorry but aspirin will be pissing in the wind if you ignore these.

Before taking an aspirin, please see your local doctor. Diabetes, high blood pressure and high cholesterol are all silent diseases which will kill you or disable you before you even know they are there.

Keith (MBChB., MRCP., FRACP)
Posted on: 25 April 2005 by Berlin Fritz
Here's a fact, Aspirin is the most successful modern drug in Human history.
Posted on: 25 April 2005 by djorg
Berlin,
What do you mind when you say successful?
Posted on: 25 April 2005 by Berlin Fritz
I mean financially for it's benefactors, like was previously said Bayer was hijacked as a Warreperations prize, as is the worlds most expensive washing powder from Henkel, namely Persil.

Fritz Von I've just got in two rather good bottles of Bordeux on your advice, I'm feeling healthier already, together with steak & melted Gorgonzola cheese & pasta Big Grin