I have holidayed in the US very many times over the past 25 or so years.
There are many wonderful places to visit, and in particular some of the many National Parks such as: the Grand Canyon; Canyonlands and Arches, Yellowstone and Yosemite to name but a few. There are many more.
There are very few iconic sights in the world that simply take ones breath away, and many that impress but at the same time disappoint just a little. The Grand Canyon, along with the Taj Mahal (not in the US, of course) are definitely two examples of the former. Simply awesome, and literally breath-taking when you see them for the first time. I can still remember the impact of my first view of the Grand Canyon when I drove into Grand Canyon Village, turned the corner and there it was. I don't recall a single holiday sight-seeing experience that has had a bigger impact on me.
I spent a lot of my time driving around the States when I was younger, but nowadays I tend to just chill out and relax when I get there, and the Gulf coast of Florida has many pristine beaches and almost perpetual good weather if you pick your time carefully. I play quite a bit of golf when on holiday, and the occasional close encounters with alligators on a number of the golf courses I play certainly tend to spice things up just a little.
Funnily enough, I have never visited New York, but I have quite a few relatives who tell me that I must do so. They love the city. San Francisco and its iconic attractions such as the Golden Gate bridge (both with and without the mist), the 'Rock' and the hippie movement legacy meant that this was a city that was pretty near the top of my own bucket list, and which I ticked off some 25 years ago and have visited subsequently on a number of other occasions. I am told by relatives and friends that Chicago is a must see city, and its own musical heritage in respect of 'Blues' music is of course second to none. I am glad I visited New Orleans on 2 or 3 occasions prior to Hurricane Katrina, but cannot vouch for how it might be nowadays.
The US is a wonderful place to visit as long as you avoid the fairly well publicised no-go areas in a few of the larger cities. I have only once felt uneasy in the States, and that was when I wondered just a little to far away from the 'French Quarter' one night in New Orleans 20 or so years ago. I had been warned, but just got a little careless. Luckily, I got away with my mistake. Some years earlier, a cousin of mine wasn't so fortunate.
I have found that the vast majority of people in the States are extremely friendly and courteous, although given recent events, I think I would probably now hesitate to broach the subject of politics in certain areas of the South with anyone I do not know well.